Printer Friendly VersionEmail A FriendAdd ThisIncrease Text SizeDecrease Text Size

Lung needle biopsy



A lung needle biopsy is a method to remove a piece of lung tissue for examination.

Alternative Names

Transthoracic needle aspiration; Percutaneous needle aspiration

How the test is performed

A chest x-ray or chest CT scan may be used to find the exact spot for the biopsy. If the biopsy is done using a CT scan, you may be lying down during the exam.

A needle biopsy of the lung may also be performed during bronchoscopy or mediastinoscopy.

You sit with your arms resting forward on a table. You should try to keep still and not cough during the biopsy. The doctor will ask you to hold your breath. The skin is scrubbed and a local pain-killing medicine (anesthetic) is injected.

The physician will make a small (about 1/8-inch) cut in the skin, and will insert the biopsy needle into the abnormal tissue, tumor, or lung tissue. A small piece of tissue is removed with the needle and sent to a laboratory for examination.

When the biopsy is done, pressure is placed over the site. Once bleeding has stopped, a bandage is applied.

A chest x-ray is taken immediately after the biopsy.

The procedure usually takes 30 - 60 minutes. Laboratory analysis usually takes a few days.

How to prepare for the test

You should not eat for 6 - 12 hours before the test. Your health care provider may tell you to avoid aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, or blood thinners such as warfarin for a period of time before the procedure. Always check with your health care provider before changing or stopping any medications.

Before a needle biopsy of the lung, a chest x-ray or chest CT scan may be performed. Sometimes, you will be given a mild sedative before the biopsy to relax you. You must sign a consent form. It is important to remain as still as possible for the biopsy and avoid coughing.

How the test will feel

You will receive an injection of anesthetic before the biopsy. This injection will sting for a moment. You will feel pressure and a brief, sharp pain when the needle touches the lung.

Why the test is performed

A needle lung biopsy is performed when there is an abnormal condition near the surface of the lung, in the lung itself, or on the chest wall.

The test is usually done to diagnose large abnormalities seen on chest x-ray or CT scan. Most often, the abnormality cannot be seen by other diagnostic techniques, such as bronchoscopy.

Normal Values

In a normal test, the tissues are normal and there is no growth of bacteria, viruses, or fungi if a culture is performed.

What abnormal results mean
  • Bacterial, viral, or fungal lung infection
  • Cancerous cells (lung cancer, mesothelioma)
  • Immune disorder
  • Pneumonia

The test may also be performed for:

What the risks are

In a very small percentage of needle biopsies, a collapsed lung or pneumothorax occurs. Usually, chest x-rays will be done. However, if the pneumothorax is large, a chest tube may need to be inserted to expand (decompress) the lung.

In rare cases, pneumothorax can be life threatening if air escapes from the lung, gets trapped in the chest, and presses on (compresses) the lungs and heart.

Whenever a biopsy is done, there is a risk of excess bleeding (hemorrhage). Some bleeding is common, and a health care provider will monitor the amount of bleeding. Rarely, major and life-threatening bleeding may occur.

A needle biopsy should NOT be performed if other tests show that you have:

Special considerations

Signs of a collapsed lung include:

If any of these occur, report them to your health care provider immediately.

Review Date: 9/13/2008
Reviewed By: Benjamin Medoff, MD, Assistant Professor of Medicine, Harvard Medical School, Pulmonary and Critical Care Unit, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission ( URAC's accreditation program is an independent audit to verify that A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among the first to achieve this important distinction for online health information and services. Learn more about A.D.A.M.'s editorial policy, editorial process and privacy policy. A.D.A.M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health on the Net Foundation (
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- 2009 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

Home Page
Why Choose Us
Website Terms of Use

Visitor & Patient Info
Patient Portal
We Speak Your Language
Patient Privacy
Contact Us

Find a Physician
Medical Services
Maimonides In the News
Directions & Parking

Medical Education
Career Opportunities
Nurses & Physicians
Staff Intranet Access
Maimonides Medical Center    |    4802 Tenth Avenue    |    Brooklyn, NY 11219    |    718.283.6000    |