Urticaria pigmentosa is characterized by few to many brownish spots which itch and, when scratched, produce welts and reddened skin. The brown spots contain cells with high levels of histamine. Individuals sometimes develop flushing and headache resulting from the massive release of histamine from these spots. This is the typical appearance of one of these spots (often referred to as a mastocytoma).
Review Date: 10/28/2008
Reviewed By: Michael Lehrer, M.D., Department of Dermatology, University of Pennsylvania Medical Center, Philadelphia, PA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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