Printer Friendly VersionEmail A FriendAdd ThisIncrease Text SizeDecrease Text Size

24-hour urine protein

 

Definition

24-hour urine protein measures the amount of protein excreted in urine over a 24-hour period.

See also: Bence-Jones protein test

Alternative Names

Urine protein - 24 hour

How the test is performed

A 24-hour urine sample is needed.

  • On day 1, urinate into the toilet when you get up in the morning.
  • Afterwards, collect all urine in a special container for the next 24 hours.
  • On day 2, urinate into the container when you get up in the morning.
  • Cap the container. Keep it in the refrigerator or a cool place during the collection period.
  • Label the container with your name, the date, the time of completion, and return it as instructed.

For an infant, thoroughly wash the area around the urethra. Open a urine collection bag (a plastic bag with an adhesive paper on one end), and place it on the infant. For males, place the entire penis in the bag and attach the adhesive to the skin. For females, place the bag over the labia. Diaper as usual over the secured bag.

This procedure may take a couple of attempts -- lively infants can move the bag, causing the urine to be absorbed by the diaper. The infant should be checked frequently and the bag changed after the infant has urinated into the bag. Drain the urine from the bag into the container provided by your health care provider.

Deliver it to the laboratory or your health care provider as soon as possible upon completion.

How to prepare for the test

Your health care provider will instruct you, if necessary, to stop taking any drugs that may interfere with the test results.

Drugs that may interfere with test results include:

  • Acetaminophen
  • Antibiotics
  • Gentamicin
  • Nonsteroidal anti-inflammatory drugs

If the collection is being taken from an infant, a couple of extra collection bags may be needed.

How the test will feel

The test involves only normal urination, and there is no discomfort.

Why the test is performed

Your doctor may order this test if you have signs or symptoms of glomerular disease, such as nephrotic syndrome, or another condition that affects kidney function.

Additional conditions under which the test may be performed include complicated UTI (pyelonephritis).

Normal Values

The normal value is less than 150 milligrams per day, or less than 10 milligrams per deciliter of urine.

Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.

What abnormal results mean

Increased levels of urinary protein may be due to:

Healthy people may have higher than normal urine protein levels after strenuous exercise or with dehydration. Some foods may affect urine protein levels.

What the risks are

The test involves normal urination and there are no risks.

Special considerations
Sometimes, in order to avoid the inconvenience and possible inaccuracy of a 24-hour urine collection, your doctor may order a test done on a just one urine sample, called the protein-to-creatinine ratio.
References

Bazari H. Approach to the patient with renal disease. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 115.


Review Date: 8/7/2009
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among the first to achieve this important distinction for online health information and services. Learn more about A.D.A.M.'s editorial policy, editorial process and privacy policy. A.D.A.M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health on the Net Foundation (www.hon.ch).
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- 2009 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
MAIMONIDES
MEDICAL CENTER


Home Page
Why Choose Us
Donations
Website Terms of Use
PATIENT
INFORMATION


Visitor & Patient Info
Patient Portal
We Speak Your Language
Patient Privacy
Contact Us
KEY
INFORMATION


Find a Physician
Medical Services
Maimonides In the News
Directions & Parking
FOR HEALTH
PROFESSIONALS


Medical Education
Career Opportunities
Nurses & Physicians
Staff Intranet Access
Maimonides Medical Center    |    4802 Tenth Avenue    |    Brooklyn, NY 11219    |    718.283.6000    |