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Cancer/Oncology:
Recruiting Patients
Phase III on Concurrent and Adjuvant Temozolomide Chemotherapy in Non-1p/19q Deleted Anaplastic Glioma. The CATNON Intergroup Trial
Dr. Bernadine Donahue/ Rolinda McIntosh
(718) 765-2693
This randomized Phase III trial is studying giving temozolomide during and/or after radiation therapy to see how well it works compared to radiation therapy alone in treating patients with anaplastic glioma.
Cancer/Oncology:
Recruiting Patients
BC200 RNA in Breast Cancer: Prognosis, Staging and Treatment Response Dr. Charusheela Andaz/ Rolinda McIntosh
(718) 765-2693
The purpose of this biomarker study is to determine whether non-coding BC200 RNA can serve as a diagnostic tool for early breast cancer detection.
Cancer/Oncology:
Recruiting Patients
Sentinel Lymph Node-II in Predicting Non-Sentinel Auxillary Lymph Node Metastasis in Women with Breast Cancer Dr. Charusheela Andaz/ Rolinda McIntosh
(718) 765-2693
The purpose of this study is to evaluate the effectiveness of Sentinel lymph node-II in predicting non-sentinel lymph node metastasis in women with breast cancer.
Cancer/Oncology:
Recruiting Patients
Low Dose Metronomic Cyclophosphamide and Methotrexate Chemotherapy in Combination with Aspirin in Patients with Stage II-III Breast Cancer Who Fail to Achieve a Pathologic Complete Response After Neoadjuvant Chemotherapy Dr. Susan Burdette-Radoux/
Rolinda McIntosh

(718) 765-2693
The purpose of this study is to test the toxicity and safety of oral low dose continuous cyclophosphamide and methotrexate chemotherapy in combination with aspirin in Stage II-III breast cancer patients who have not achieved a pathologic complete response after surgery and radiotherapy.
Cancer/Oncology:
Recruiting Patients
A Randomized Phase III Trial of the Value of Early Local Therapy for the Intact Primary Tumor in Patients with Metastatic Breast Cancer (ECOG 2108, NCI) Dr. Susan Burdette-Radoux/
Rolinda McIntosh

(718) 765-2693
This randomized Phase III trial is studying early surgery to see how well it works compared to standard palliative therapy in treating patients with stage IV breast cancer.
Cancer/Oncology: Recruiting Patients
A Phase III, Randomized Clinical Trial of Standard Adjuvant Endocrine Therapy +/- Chemotherapy in Patients with 1-3 Positive Nodes, Hormone Receptor-Positive and HER-2 Negative Breast Cancer with Recurrence Score (RS) of 25 or Less Dr. Susan Burdette-Radoux/
Rolinda McIntosh

(718) 765-2693
This Phase III clinical trial is studying how well giving tamoxifen citrate, anastrozole, letrozole, or exemestane with or without chemotherapy works in treating patients with invasive breast cancer.
Cancer/Oncology: Recruiting Patients A Phase III Trial of Accelerated Whole Breast Irradiation with Hypofractionation Plus Concurrent Boost Versus Standard Whole Breast Irradiation Plus Sequential Boost for Early-Stage Breast Cancer Dr. Amy Young/  
Rolinda McIntosh

(718) 765-2693
This randomized Phase III trial studies how well high-dose radiation therapy works compared to standard radiation therapy in treating patients with early-stage breast cancer that was removed by surgery.
Cancer/Oncology: Recruiting Patients A Randomized Phase II Study of Irinotecan and Cetuximab with or without the Anti-Angiogenic Antibody, Ramucirumab (IMC-1121B), in Advanced, K-ras Wild-type Colorectal Cancer Following Progression on Bevacizumab-Containing Chemotherapy Dr. William Solomon/ Rolinda McIntosh
(718) 765-2693
This randomized Phase II trial is studying the side effects and how well giving cetuximab and irinotecan hydrochloride with or without ramucirumab work in treating patients with advanced colorectal cancer with progressive disease after treatment with bevacizumab-containing chemotherapy.
Cancer/Oncology: Recruiting Patients Prevalence and Molecular Screening for Hereditary Non-Polyposis Colorectal Cancer (NPCC) Syndrome in Asian Patients Dr. Yiquing Xu/   
Rolinda McIntosh

(718) 765-2693
The purpose of this study is to evaluate the presence of Hereditary Non-Polyposis Colorectal Cancer Syndrome in Asiant Patients with colon, gastric, and/or endometrial cancer and to identify genetic mutation founders in the ethnic group.
Cancer/Oncology: Recruiting Patients A Phase III Randomized, Double-Blind Trial of Chemoembolization with or without Sorafenib in Unresectable Hepatocellular Carcinoma (HCC) in Patients with or without Vascular Invasion Dr. Yiquing Xu/   
Rolinda McIntosh

(718) 765-2693
This randomized Phase III trial is studying chemoembolization and sorafenib tosylate to see how well they work compared with chemoembolization alone in treating patients with liver cancer that cannot be removed by surgery
Cancer/Oncology: Recruiting Patients Phase II Trial of Combination Pemetrexed (Alimta) and Carboplatin (Paraplatin) in Platinum Sensitive Recurrent Ovarian, Primary Peritoneal, and Fallopian Tube Carcinoma Dr. Alan Astrow/  
 Rolinda McIntosh

(718) 765-2693
The purpose of this study is to determine the effects (good and bad) the combination of carboplatin and pemetrexed have on patients with recurrent ovarian, peritoneal, or fallopian tube cancer.
Cancer/Oncology: Recruiting Patients A Phase III Study of Post Operative Radiation Therapy (IMRT) +- Cetuximab for Locally-Advanced Resected Head and Neck Cancer Dr. Jay Cooper/   
Rolinda McIntosh

(718) 765-2693
The purpose of this clinical trial is to test whether the addition of cetuximab to radiation therapy will improve overall survival (OS) in postoperative patients with intermediate risk following surgery
Cancer/Oncology: Recruiting Patients SA Case-Control Study of Head and Neck Cancer: A Study of Gene and Environment Risk Factors Dr. Jay Cooper/   
Rolinda McIntosh

(718) 765-2693
The purpose of this study is to identify whether genetic variations in enzymes which metabolize tobacco smoke and alcohol contributes to differences in susceptibility to head and neck cancers.
Cancer/Oncology: Recruiting Patients A Randomized Phase II Study of Adjuvant Concurrent Radiation and Chemotherapy Versus Radiation Alone in Resected High-Risk Malignant Salivary Gland Dr. Jay Cooper/  
Rolinda McIntosh

(718) 765-2693
The purpose of this study is to acquire preliminary data comparing postoperative radiotherapy alone to concurrent chemotherapy and radiation using weekly cisplatin.
Cancer/Oncology: Recruiting Patients Phase III Trial of Radiotherapy Plus Cetuximab Versus Chemoradiotherapy in HPV-Associated Oropharynx Cancer Dr. Jay Cooper/   
Rolinda McIntosh

(718) 765-2693
This Phase III trial is studying radiation therapy with cisplatin or cetuximab to see how well it works in treating patients with oropharyngeal cancer.
Cancer/Oncology: Recruiting Patients A Phase III Trial Evaluating Both Erlotinib and Chemoradiation as Adjuvant Treatment for Patients with Resected Head of Pancreas Adenocarcinoma Dr. Bernadine Donahue/ Rolinda McIntosh
(718) 765-2693
This randomized Phase III trial is studying gemcitabine hydrochloride and erlotinib hydrochloride to see how well they work compared with gemcitabine hydrochloride alone followed by the same chemotherapy regimen with or without radiation therapy and capecitabine or fluorouracil in treating patients with pancreatic cancer that was removed by surgery.
Cancer/Oncology:
Recruiting Patients
Is the ECOG Performance Status Evaluation Sufficient to Predict Tolerance of Chemotherapy in Elderly Patients Dr. William Solomon/ Rolinda McIntosh
(718) 765-2693
The purpose of this study is to evaluate whether ECOG performance scores are sufficient to predict tolerance of chemotherapy in elderly cancer patients.
Cancer/Oncology: Recruiting Patients Serum VEGF Levels in Patients Developing Hypertension or Proteinuria After Treatment with Anti-VEGF Antibody Bevacizumab for Metastatic Cancers Dr. Yiquing Xu/   
Rolinda McIntosh

(718) 765-2693
The purpose of this study is to compare the levels of vascular endothelial growth factor (VEGF) in patients developing hypertension and proteinuria with those patients without such side effects after Bevacizumab treatment and to correlate the level of VEGF with tumor growth and progression.
Cancer/Oncology: Recruiting Patients Correlation of Serum and Plasma VEGF Levels with Thrombocytopenia of Various Etiology, a Biomarker Study Dr. Yiquing Xu/   
Rolinda McIntosh

(718) 765-2693
The purpose of this study is to evaluate vascular endothelial growth factor (VEGF) levels in patients with thrombocytopenia of various etiologies at the time of diagnosis.
Cancer/Oncology: Recruiting Patients PREDICT: A Multi-Center Study in Patients Undergoing Anthracycline-Based Chemotherapy to Assess the Effectiveness of Using Biomarkers to Detect and Identify Cardiotoxicity and Describe Treatment Dr. William Solomon/ Rolinda McIntosh
(718) 765-2693
The goal of this clinical research study is to learn if certain biomarker testing on blood samples can help to detect heart damage that may occur during chemotherapy. Biomarkers are chemical "markers" found in the blood that may be related to heart function. High levels of these markers may be
Cancer/Oncology: Recruiting Patients A Phase I/II Trial of a Combination of Paclitaxel and Trastuzumab with Daily Irradiation or Paclitaxel Alone with Daily Irradiation Following Transurethral Surgery for Non-Cystectomy Candidates with Muscle-Invasive Bladder Cancer Dr. William Solomon/ Rolinda McIntosh
(718) 765-2693
This Phase I/II trial is studying the side effects of giving paclitaxel together with radiation therapy with or without trastuzumab and to see how well it works to kill any remaining tumor cells in patients who have undergone surgery for bladder cancer.
Cancer/Oncology: Recruiting Patients A Phase III Randomized Trial of Adjuvant Chemotherapy With or Without Bevacizumab for Patients with Completely Resected Stage IB (>- 4 cm) - IIIA Non-Small Cell Lung Cancer (NSCLC) Dr. William Solomon/ Rolinda McIntosh
(718) 765-2693
This randomized Phase III trial is studying chemotherapy and bevacizumab to see how well they work compared to chemotherapy alone in treating patients with stage IB, stage II, or stage IIIA non-small cell lung cancer that was removed by surgery.
Cancer/Oncology: Recruiting Patients Randomized Phase III Study of Maintenance Therapy with Bevacizumab, Pemetrexed, or a Combination of Bevacizumab and Pemetrexed Following Carboplatin, Paclitaxel and Bevacizumab for Advanced Non-Squamous Non-Small Cell Lung Cancer (NSCLC) Dr. Kevin Becker/
Rolinda McIntosh

(718) 765-2693
This randomized Phase III trial is studying bevacizumab and pemetrexed disodium alone or in combination after induction therapy to see how well they work in treating patients with advanced non-squamous non-small cell lung cancer.
Cancer/Oncology: Recruiting Patients Paclitaxel With or Without Carboplatin and/or Bevacizumab Followed By Doxorubicin and Cyclophosphamide in Treating Patients With Breast Cancer That Can Be Removed by Surgery Dr. Alan Astrow/
Rolinda McIntosh

(718) 765-2693
This randomized Phase II trial is studying how well giving paclitaxel with or without carboplatin and/or bevacizumab followed by doxorubicin and cyclophosphamide works in treating patients with breast cancer that can be removed by surgery.
Pediatric Cancer/ Oncology:
Recruiting Patients
A 5-year, Prospective, Non-interventional, Multicenter Registry in Sickle Cell Disease (SCD) Patients Ludvico Guarini/
Gennie Wyatt

(718) 283-7374.
This is a long term observational study in sickle cell disease whose aim is to  enhance the understanding of the disease patterns, current transfusion practices, treatments and outcomes in sickle cell disease.
Cardiology:
Recruiting Patients
Hyponatremia Registry for Patients With Euvolemic and Hypervolemic Hyponatremia Dr. Norbert Moskovits/ Gwendolyn Tan-Augenstein (718) 283-7064 The registry is a multi-center, prospective, observational study designed to collect data in patients with euvolemic and hypervolemic hyponatremia in the hospital setting.
Cardiology:
Recruiting Patients
The PACE-MI Registry Study Dr. Jacob Shani/ Gwendolyn Tan-Augenstein
(718) 283-7064
The purpose of the PACE-MI registry is to a) analyze beta-blocker dose response effect on outcome over two years; and b) Explore gender and minority differences in beta-blocker utilization and outcomes.
Psychiatry:
Recruiting Patients
Omega-3 Fatty Acids as an Adjunctive Therapy for Treatment in Attention-Deficit Hyperactivity Disorder (ADHD)
Dr. Jose M. Torrijos/
Jose Torrijos, MD

(718) 283-8828
This study is a prospective, randomized, placebo controlled, double blind trial comparing the response to treatment in children with a diagnosis of ADHD treated with stimulants and placebo vs. children with a diagnosis of ADHD on stimulants plus Omega-3 fatty acids.
Surgery:
Recruiting Patients
The Use of Fluorescent Imaging for Intraoperative Cholangiogram During Laparoscopic Cholecystectomy Dr. Danny A Sherwinter/
Danny Sherwinter, MD

(718) 283-7952
The purpose of this study is to evaluate whether a fluorescent dye and a special infrared camera can assist with the identification of the important structures during laparoscopic cholecystectomy. This finding may assist surgeons to perform laparoscopic cholecystectomy in less time and in a safer fashion than standard laparoscopic cholecystectomy.
Surgery:
Recruiting Patients
Fluorescent Evaluation of Colorectal Anastamoses Dr. Danny A Sherwinter/
Danny Sherwinter, MD

(718) 283-7952
The purpose of this study is to utilize a special camera to evaluate the blood supply of the bowel. This new system is called the Spy-scope. This system may assist surgeons in reducing the occurrence of leaks.
Emergency Medicine:
Recruiting Patients
Improving Pain and Function in Hip Fracture Dr. Eitan Dickman/
Antonios Likourezos

(718) 283-6896
The purpose of this study is to compare two different methods of treating pain after a hip fracture.
Radiology:
Active, Not Recruiting Patients
Primovist / Eovist in Renally Impaired Patients
Dr. Mark Flyer/
Not Recruiting Patients
This purpose of this trial is to use contrast agents Primovist / Eovist to assess the potential risk of developing Nephrogenic Systemic Fibrosis (NSF) in patients with renal impairment.
Neurology:
Active, Not Recruiting Patients
 JCV Antibody Program (STRATIFY-2) Dr. Marshall Keilson/ 
Not Recruiting Patients
 Define the sero prevalence of JCV Antibody in the MS population and potentially stratify patients into lower or higher risk for developing PML based on antibody status.
 
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Maimonides Medical Center    |    4802 Tenth Avenue    |    Brooklyn, NY 11219    |    718.283.6000